Director, Target Profiling, Translational Research

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About the position

Responsibilities

  • Develop and validate methodologies, including ctDNA, MRD, and protein-based assays, to monitor disease progression and therapeutic efficacy.
  • Lead the development of stage-appropriate CDx assays for precision patient profiling.
  • Manage the implementation of flow cytometry and advanced profiling techniques to stratify patient populations.
  • Collaborate with Preclinical Program teams and Clinical Biomarker teams to define and implement translational strategies.
  • Stay updated on scientific advancements in precision targeting and companion diagnostics.
  • Contribute to the translational research team strategy, fostering innovation and excellence.
  • Oversee relationships with CROs and internal labs for assay development and validation studies.
  • Mentor and develop junior scientists within the translational research team.
  • Act as a scientific liaison for internal and external collaborators in the oncology space.
  • Contribute to regulatory submissions, scientific publications, and presentations.

Requirements

  • Ph.D. in a relevant scientific discipline (e.g., oncology, immunology) with a minimum of 10 years of experience in translational research.
  • Proven expertise in developing and validating CDx assays and disease monitoring tools.
  • Strong background in flow cytometry, ctDNA sequencing, MRD methodologies, and protein-based assays.
  • Excellent communication and collaboration skills, with experience in cross-functional teams.
  • A results-driven mindset capable of thriving in a fast-paced environment.
  • Demonstrated ability to innovate translational approaches for novel therapeutic concepts.
  • Experience with regulatory submissions and interactions with health authorities is highly desirable.
  • Strong project management and organizational skills.

Nice-to-haves

  • A strong publication record in peer-reviewed journals, particularly in cancer immunotherapy or autoimmunity.

Benefits

  • Highly competitive medical, dental, and vision coverage options.
  • Flexible Spending Accounts for medical and dependent care expenses.
  • Lifestyle Spending Account funds for personal enrichment activities.
  • Family care benefits, including subsidized back-up care options.
  • Free premium access to fitness, nutrition, and mindfulness classes.
  • Exclusive preferred pricing on Peloton fitness equipment.
  • Adoption and family-planning benefits.
  • Generous paid time off, including vacation, sick time, and holidays.
  • Volunteer time to participate in community activities.
  • Discretionary year-end shutdown and paid sabbatical after 5 years.
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave.
  • 401k match and Financial Planning tools.
  • Moderna-paid Life, LTD, and STD insurance coverages.
  • Complimentary concierge service for home services and travel booking.
  • Free parking or subsidized commuter passes.
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